Asymmetric interface.

High flow therapy - enhanced. 


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An evolution in our understanding of high flow therapy over two decades has resulted in the asymmetric F&P Optiflow DuetTM interface.

Using an asymmetric design, i.e., one small prong and one large we are able to amplify key mechanisms of action, to not only deliver but enhance high flow therapy.1   

Asymmetric interface. 

High flow therapy - enhanced.

The asymmetric design provides greater total occlusion which increases pressure1.

1. Tatkov S, et al. J Appl Physiol. 2023; 134(2):365-377

Dead space clearance is increased by creating unidirectional flow which purges expired gas1.

1. Tatkov S, et al. J Appl Physiol. 2023; 134(2):365-377

Pressure.1 Dead Space Clearance.1 Comfort.2

This short video explains the key mechanisms of action of high flow, driven by flow and humidification.

Why is the Reduction of Dead Space so important?

Learn a bit more about one of the least understood nasal high flow Mechanisms of Action.

The Optiflow Duet interface range

Small OPT962

Medium OPT964

Large OPT966

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  1. Tatkov S, Rees M, Gulley A, et al. Asymmetrical nasal high flow ventilation improves clearance of CO, from the anatomical dead space and increases positive airway pressure. J Appl Physiol. 2023; 134(2):365-377. 
  2. Boscolo A, Pettenuzzo T, Zarantonello F, et al. Asymmetrical high-flow nasal cannula performs similarly to standard interface in patients with acute hypoxemic post-extubation respiratory failure: a pilot study. BMC Pulm Med. 024; 24:21. Study conducted on patients with post-extubation hypoxemic acute respiratory failure.

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